Grey’s Anatomy Season 21 Faces Major Casting Shakeup: Who’s Leaving and What It Means for the Future

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Quick Summary

Grey’s Anatomy Season 21 is undergoing significant changes as two regular cast members, Jake Borelli and Midori Francis, are set to leave. Borelli, who plays Levi Schmitt, and Francis, who portrays Mika Yasuda, will return briefly to conclude their characters’ storylines. These departures come amid budget cuts and shifts in the show’s direction. While this may affect the show’s dynamic and LGBTQ+ representation, new characters and fresh storylines are expected to keep the series moving forward. Fans can anticipate an evolving ensemble as Grey’s Anatomy continues its legacy with exciting changes in the upcoming season.

Introduction

The long-running medical drama Grey’s Anatomy has seen its fair share of cast changes over the years, but the latest news about Season 21 might be one of the most significant shakeups yet. As fans are still enjoying Season 20, ABC has already revealed some major changes that will impact the upcoming season. These changes include the exit of not one, but two regular stars, with Jake Borelli (Levi Schmitt) and Midori Francis (Mika Yasuda) both leaving the show. But what exactly does this mean for the future of Grey’s Anatomy?

In this blog post, we’ll dive deep into the reasons behind these departures, explore how the shakeup will affect the show’s dynamic, and what fans can expect from the upcoming season. Whether you’re a longtime fan or new to the series, keep reading to stay updated on everything you need to know about the latest casting changes.


Why Is Grey’s Anatomy Season 21 Facing Major Casting Changes?

Grey’s Anatomy has been on the air for nearly two decades, so it’s no surprise that cast changes are part of the territory. However, the upcoming changes in Season 21 are particularly notable due to a few key factors, including budget cuts and shifting dynamics within the show’s ensemble.

The Impact of Budget Cuts on Grey’s Anatomy

As with many long-running TV shows, Grey’s Anatomy has had to make adjustments to its budget for the upcoming seasons. The pressure to reduce costs has resulted in fewer episodes for the regular cast, which in turn impacts their contracts. Instead of renegotiating for fewer episodes, some actors may choose to leave the show altogether.

This kind of change is never easy, especially when beloved characters are involved. Jake Borelli and Midori Francis’s exits are directly tied to these budget adjustments, as the show attempts to remain financially viable while continuing to produce high-quality drama for its audience.

The Transition to a New Timeslot and Its Implications

Another factor contributing to the cast changes is the show’s move to a new timeslot. Starting in Season 21, Grey’s Anatomy will air at 10 p.m. EST, an hour later than its usual Thursday 9 p.m. slot. This change could have a significant impact on viewership, as many fans are accustomed to the earlier timeslot. The shift in time might result in lower ratings, and the show’s producers could be rethinking its structure as a way to cope with potential viewer loss.


Who Are the Stars Leaving Grey’s Anatomy in Season 21?

While many actors have come and gone over the years, the departure of Jake Borelli and Midori Francis is particularly impactful. Their characters have become integral parts of Grey’s Anatomy’s ensemble, and their exits will leave big shoes to fill.

Jake Borelli’s Exit: Levi’s Final Story Arc

Jake Borelli, who has played the lovable and often misunderstood Dr. Levi Schmitt, will be departing as a series regular in Season 21. Levi’s character has undergone significant development over the years, from struggling with self-acceptance to finding love and embracing his identity.

Borelli’s exit will wrap up Levi’s storyline, providing closure to a character who has become a fan favorite, especially with the show’s emphasis on LGBTQ+ representation. Sources indicate that Borelli will return for a few episodes to tie up loose ends, giving fans a satisfying conclusion to Levi’s story.

Fun Fact: Levi’s coming-out arc was one of the most praised storylines in recent seasons. It was a breakthrough moment for both the character and the series, as it helped broaden the conversation around LGBTQ+ issues in healthcare.

Midori Francis Leaves as Intern Mika Yasuda

Midori Francis, who portrays the insightful and grounded intern Mika Yasuda, is also set to leave Grey’s Anatomy in Season 21. Mika’s departure is described as amicable, with Francis seeking to take the next step in her career.

Mika has played a pivotal role in the intern class over the past two seasons, often acting as a mediator among her fellow interns. Her ability to bring the group together, especially during moments of personal conflict, has made her a valuable asset to the show. Mika’s relationship with Taryn Helm was also an important storyline for LGBTQ+ representation, and her exit will be a loss for many fans who appreciated the portrayal of a healthy, developing same-sex relationship.


What Does This Casting Shakeup Mean for Grey’s Anatomy Season 21?

With the departures of both Jake Borelli and Midori Francis, Grey’s Anatomy is going through a significant casting shakeup that will have far-reaching implications for the show.

The Future of the Grey’s Anatomy Ensemble Cast

Grey’s Anatomy has always thrived with its ensemble cast, which allows for multiple storylines to unfold at once. The departure of two regulars means that the remaining cast members, including characters like Meredith, Owen, and Teddy, will have to carry even more of the show’s narrative weight.

However, the exits could also open the door for new characters to join the hospital. Grey’s Anatomy has a long history of introducing fresh faces, and with the show’s ever-evolving roster, it’s likely that Season 21 will feature new interns or doctors who could shake things up in a big way.

In fact, the departure of Mika Yasuda could create a void that another character might step into, perhaps adding a new dynamic to the intern group. With the show’s history of successful character introductions (e.g., Meredith’s original group of interns), fans are hopeful that Season 21 will bring in some fresh energy to balance out the losses.

The Effect of Departures on Storylines

The loss of these two characters will undoubtedly affect ongoing storylines, particularly in the intern class. Mika’s role as a supportive and level-headed figure will be missed, and it will be interesting to see how the remaining interns—Simone, Lucas, Jules, and Blue—handle the absence of their teammate. Without Mika, the interns may face challenges without her mediation, which could result in more personal drama and growth for each character.

Additionally, Levi’s exit means that some of the show’s ongoing LGBTQ+ storylines will likely come to a close. Fans of Levi and his relationship with his colleagues will need to brace for the emotional goodbye, but the hope is that his story will be wrapped up in a way that feels true to his character and the Grey’s Anatomy legacy.


Stay tuned as we continue exploring the potential impact of these casting changes on Grey’s Anatomy, including what fans can expect in the upcoming season, how the show may adapt, and what the future holds for the series as a whole.

What’s Next for Grey’s Anatomy? Could More Cast Members Leave?

As we’ve seen with the departure of Jake Borelli (Levi Schmitt) and Midori Francis (Mika Yasuda), Grey’s Anatomy is no stranger to cast changes. Given the budget cuts, it’s possible that more actors could leave or appear in fewer episodes in the upcoming seasons.

Could More Cast Members Exit?

With the ongoing financial adjustments, Grey’s Anatomy has had to reduce its budget, which could lead to further changes in the cast. Longtime stars like Kevin McKidd (Owen Hunt), Kim Raver (Teddy Altman), and Chandra Wilson (Miranda Bailey) could potentially see their roles reduced. Instead of leaving entirely, these actors may take on fewer episodes per season, similar to Ellen Pompeo’s role in recent years.

While it’s unlikely that any of the core characters will completely exit, the possibility of more departures is still very real. The show’s ability to keep its fans engaged, even with changes to the core ensemble, will be tested in the upcoming seasons.


How Will the Departure of These Characters Affect Grey’s Anatomy’s Legacy?

Grey’s Anatomy is not just a medical drama; it’s a cultural institution, having tackled important issues over its two-decade run. With the exit of key characters, it’s essential to examine how this might impact the show’s legacy.

The End of an Era

Jake Borelli and Midori Francis’s departures mark the end of an era for Grey’s Anatomy. Levi Schmitt and Mika Yasuda both contributed significantly to the diversity and complexity of the show, particularly in terms of LGBTQ+ representation. Their exits may signal the end of certain storylines, but they also make room for new characters and new narratives that will continue to evolve the show’s legacy.

Fans who have followed the series for years may feel the emotional impact of losing characters they’ve grown attached to. However, Grey’s Anatomy has always been able to reinvent itself, and this shakeup may just be another step in the evolution of the show.

How These Departures Align with the Show’s Themes

The departures are in line with one of the key themes of Grey’s Anatomy: the constant change and growth of both the characters and the hospital itself. Throughout the years, we’ve witnessed beloved characters leave and new ones arrive, from George O’Malley to Lexie Grey to April Kepner.

While these exits may leave a void, Grey’s Anatomy has proven time and time again that it can carry on through transitions while remaining relevant and impactful.


What Can Fans Expect from Grey’s Anatomy Season 21?

With the upcoming changes in the cast, fans are naturally wondering what to expect from Grey’s Anatomy in Season 21. Here’s what we know so far:

The Focus on New Characters

Season 21 will likely see the introduction of new interns or attending physicians to fill the gaps left by Borelli and Francis. New characters will help revitalize the show’s energy, offering fresh dynamics and storylines. These new additions could offer a much-needed boost to the ensemble cast, keeping the show dynamic and exciting.

More Focus on Established Characters

While new faces will join the roster, the core cast members will remain at the heart of Grey’s Anatomy. Meredith Grey, Miranda Bailey, Owen Hunt, and Teddy Altman will continue to be the anchors of the series. Their personal and professional lives will remain central to the drama, though their stories may evolve as they deal with the changes around them.

Expect some of the older characters to step up into more prominent roles, especially as the medical situations at Grey Sloan Memorial become more complex. The hospital itself may see new challenges, which will test the resolve of both the old and new characters.

The Legacy of Levi and Mika

Although Borelli and Francis are leaving, their characters will not be forgotten. Both Levi and Mika have made a lasting impact on the series, and their storylines will likely be wrapped up in a way that honors their contribution to Grey’s Anatomy. For fans of Levi and Mika, this will be a bittersweet farewell, but it also sets the stage for new characters and new relationships.


How Can You Stay Updated on Grey’s Anatomy Season 21?

Fans of Grey’s Anatomy will want to stay in the loop as more details about Season 21 unfold. Here’s how you can stay updated:

Follow Official Social Media Accounts

ABC, the network behind Grey’s Anatomy, regularly updates its followers on social media platforms like Instagram, Twitter, and Facebook. These accounts often provide sneak peeks, behind-the-scenes content, and important announcements about the cast and episodes.

Subscribe to Entertainment News Sites

For the latest news, interviews, and updates on Grey’s Anatomy, be sure to follow reputable entertainment websites such as:

These sites frequently publish exclusive interviews and inside scoops about the cast and production.

Join Grey’s Anatomy Fan Communities

If you’re craving discussions with fellow Grey’s Anatomy fans, consider joining online fan communities. Platforms like Reddit (r/GreysAnatomy) and dedicated Facebook groups are great ways to stay informed and share opinions with others. Plus, these groups often share updates as soon as they drop, making it easy to stay ahead of the curve.


Conclusion: The Future of Grey’s Anatomy and What to Expect in Season 21

Grey’s Anatomy has become synonymous with character-driven storytelling, medical drama, and a commitment to tackling complex, real-world issues. While Season 21 will undoubtedly be a period of transition, the show’s enduring legacy will remain intact, bolstered by the introduction of new characters, fresh storylines, and the continued growth of its core cast.

The departures of Jake Borelli and Midori Francis will be felt deeply, particularly by fans who have grown attached to Levi Schmitt and Mika Yasuda. However, the show’s ability to evolve and reinvent itself has always been one of its greatest strengths. The introduction of new faces will offer exciting opportunities, while the seasoned cast members will continue to provide the emotional depth and stability that Grey’s Anatomy is known for.

As we move forward into the unknown of Season 21, one thing is certain: Grey’s Anatomy will continue to captivate and surprise its viewers, offering the drama, heart, and medical cases we’ve come to love. Fans should keep their eyes peeled for more updates, as we’re sure to see some unforgettable moments in the season ahead.

Grey’s Anatomy


TV-14 | Drama | Romance
A medical drama series centered on surgical interns, residents, and attendings at Grey Sloan Memorial Hospital. Created by Shonda Rhimes, the show explores the complexities of medical cases and the interpersonal relationships among the hospital staff.

Where to Watch:
Season | Stream | Rent | Buy | Not available

Availability in US
Cast:
Ellen Pompeo, Chandra Wilson, James Pickens Jr., Justin Chambers, Kevin McKidd, Jesse Williams, Bokhee An, Camilla Luddington, Patrick Dempsey, Sara Ramirez, Jessica Capshaw, Sandra Oh, Caterina Scorsone, Sarah Drew, Kelly McCreary, Kim Raver, Jason George, Eric Dane, Giacomo Gianniotti, Jake Borelli, Katherine Heigl, Jerrika Hinton, Chyler Leigh, Chris Carmack, T.R. Knight, Debbie Allen, Jaicy Elliot, Anthony Hill, Kate Walsh, Greg Germann, Isaiah Washington, Aniela Gumbs, Martin Henderson, Payton Silver, Gaius Charles, Tessa Ferrer, Stefania Spampinato, Alex Landi, Scott Speedman, Mark Saul, Nicole Rubio, Richard Flood, Ryder Goodstadt, Steven W. Bailey, Adelaide Kane, Alexis Floyd, Harry Shum Jr., Midori Francis, Niko Terho
Character(s):
Dr. Meredith Grey, Dr. Miranda Bailey, Dr. Richard Webber, Dr. Alex Karev, Dr. Owen Hunt, Dr. Jackson Avery, Nurse Bokhee, Dr. Jo Wilson, Dr. Derek Shepherd, Dr. Callie Torres, Dr. Arizona Robbins, Dr. Cristina Yang, Dr. Amelia Shepherd, Dr. April Kepner, Dr. Maggie Pierce, Dr. Teddy Altman, Dr. Ben Warren, Dr. Mark Sloan, Dr. Andrew DeLuca, Dr. Levi Schmitt, Dr. Izzie Stevens, Dr. Stephanie Edwards, Dr. Lexie Grey, Dr. Atticus Lincoln, Dr. George O’Malley, Dr. Catherine Fox, Dr. Taryn Helm, Dr. Winston Ndugu, Dr. Addison Montgomery, Dr. Thomas Koracick, Dr. Preston Burke, Zola Gray Shepard, Dr. Nathan Riggs, Dr. Knox, Dr. Shane Ross, Dr. Leah Murphy, Dr. Carina DeLuca, Dr. Nico Kim, Dr. Nick Marsh, Intern Steve, Paramedic Nicole, Dr. Cormac Hayes, Derek Bailey Shepherd, Joe, Dr. Jules Millin, Dr. Simone Griffith, Dr. Benson Kwan, Dr. Mika Yasuda, Dr. Lucas Adams
Release Date: March 27, 2005
Seasons: 21
Network: ABC
Writers: Shonda Rhimes, Julie Wong, Jen Klein, Tameson Duffy, Meg Marinis
Directors: Rob Corn, Kevin McKidd, Debbie Allen, Chandra Wilson, Allison Liddi-Brown, Jeannot Szwarc, Tony Phelan
Main Genre: Drama
Creator(s): Shonda Rhimes, Michelle Lirtzman
Where To Watch: Hulu

Frequently Asked Questions

Here are some of the most frequently asked questions about Mika Yasuda’s departure from Grey’s Anatomy and her character’s journey. If you’re looking for more information or have questions about her story arc, you’ve come to the right place!

Frequently Asked Questions

As Grey’s Anatomy prepares for another season with major casting changes, fans are left with plenty of questions. Here are some of the most common ones about Season 21 and the future of the series.

1. Why are Jake Borelli and Midori Francis leaving Grey’s Anatomy in Season 21?

Jake Borelli (Levi Schmitt) and Midori Francis (Mika Yasuda) are both leaving Grey’s Anatomy due to budget cuts and shifts in the show’s direction. However, their exits are expected to be amicable, and both actors will return in a limited capacity to wrap up their characters’ storylines.

2. Will other main characters leave Grey’s Anatomy in Season 21?

While it’s not confirmed, there are rumors that more cast members could leave or have reduced roles due to the budget cuts. Longtime stars like Kevin McKidd (Owen Hunt) and Kim Raver (Teddy Altman) may also appear in fewer episodes.

3. How will the departure of Jake Borelli and Midori Francis affect the show?

The exits of these two characters will certainly have an impact, especially in terms of representation and character dynamics. However, Grey’s Anatomy has a long history of evolving its cast and bringing in new characters, so it’s likely the show will continue with fresh faces and stories while keeping the core cast intact.

4. Will Grey’s Anatomy continue beyond Season 21?

Though nothing is confirmed beyond Season 21, Grey’s Anatomy has been a staple of TV for over 20 years, and its renewal is likely as long as it continues to captivate audiences. The show’s ability to reinvent itself with new storylines and characters has kept it relevant, so there’s still potential for more seasons.

5. Who will replace Jake Borelli and Midori Francis as series regulars?

As of now, there is no official word on who will take the place of Borelli and Francis. However, we can expect new characters to fill the gaps and perhaps even new interns or attending physicians who will shake up the dynamics at Grey Sloan Memorial.

6. How can I stay updated on Grey’s Anatomy Season 21?

You can follow official social media accounts like the Grey’s Anatomy Instagram, Twitter, and Facebook pages for updates. You can also subscribe to entertainment websites such as Deadline, Variety, and TVLine for exclusive news, and join online fan communities for real-time discussions.

Author’s Note

As a long-time fan of Grey’s Anatomy, it’s always bittersweet to watch beloved characters come and go. The departures of Jake Borelli and Midori Francis in Season 21 mark yet another chapter in the evolving narrative of the show. While it’s sad to see these talented actors leave, it also opens the door for new and exciting storylines, just as Grey’s Anatomy has done so many times before.

I’ve spent a lot of time following the ups and downs of the series, from the early days with Meredith and Derek to the more recent shifts in the cast. One thing is clear: Grey’s Anatomy has an incredible ability to reinvent itself, and I’m excited to see how the show continues to evolve.

As we dive into the changes coming in Season 21, it’s important to remember that the heart of Grey’s Anatomy has always been its characters—whether old or new. With each departure, new opportunities arise for fresh faces and storylines to shine.

I hope this article helps you better understand the casting shakeup and what it means for the future of the show. As always, I’ll be keeping a close eye on the latest developments and looking forward to another season full of drama, emotion, and heart-stopping moments.

If you have any thoughts or questions, feel free to leave a comment below! Let’s keep the conversation going as we prepare for what’s next on Grey’s Anatomy.

Mary Linda

Mary Linda is the lead author at Celebrity To People, where she brings her expertise and passion for celebrity journalism to the forefront. With a distinguished career spanning five years in the writing industry, Mary has contributed to numerous reputable publications before finding her niche in the world of celebrity news and stories.

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